It's 1980 in New York City, and nowhere is the city's glamour and energy better reflected than in the burgeoning Harlem ball scene, where seventeen-year-old Angel first comes into her own. Burned by her traumatic past, Angel is new to the drag world, new to ball culture, and has a yearning inside of her to help create family for those without. When she falls in love with Hector, a beautiful young man who dreams of becoming a professional dancer, the two decide to form the House of Xtravaganza, the first-ever all Latino-house in the Harlem ball circuit. But when Hector dies of AIDS-related complications, Angel must bear the responsibility of tending to their house alone. As mother of the house, Angel recruits Venus, a whip-fast trans girl who dreams of finding a rich man to take care of her; Juanito, a quiet boy who loves fabrics and design; and Daniel, a butch queen who accidentally saves Venus's life. The Xtravaganzas must learn to navigate sex work, addiction, and persistent abuse, leaning on one another as bulwarks against a world that resists them. All are ambitious, resilient, and determined to control their own fates, even as they hurtle toward devastating consequences.